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1

Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy

Chantal Le Guellec, Matthias Büchler, Bruno Giraudeau, Yannick Le Meur, Jean-Emmanuel Gakoué, Yvon Lebranchu, Pierre Marquet, Gilles Paintaud

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 136 KB

english, 2002

2

Pharmacokinetic Studies in Neonates: The Utility of an Opportunistic Sampling Design

Leroux, Stéphanie, Turner, Mark A., Guellec, Chantal Barin-Le, Hill, Helen, van den Anker, Johannes N., Kearns, Gregory L., Jacqz-Aigrain, Evelyne, Zhao, Wei

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 982 KB

english, 2015

3

Iohexol clearance in unstable critically ill patients: a tool to assess glomerular filtration rate

Salmon-Gandonnière, Charlotte, Benz-de Bretagne, Isabelle, Mercier, Emmanuelle, Joret, Aurélie, Halimi, Jean-Michel, Ehrmann, Stephan, Barin-Le Guellec, Chantal

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2016

Language:

english

File:

PDF, 719 KB

english, 2016

4

Niveau de preuve du suivi thérapeutique pharmacologique du méthotrexate au décours de son administration à haute-dose

Le Guellec, Chantal, Blasco, Hélène, Benz, Isabelle, Hulin, Anne

Journal:

Year:

2010

Language:

french

File:

PDF, 365 KB

french, 2010

5

Ischemia/reperfusion-associated tubular cells injury in renal transplantation: Can metabolomics inform about mechanisms and help identify new therapeutic targets?

Guellec, Chantal Barin-Le, Largeau, Bérenger, Bon, Delphine, Marquet, Pierre, Hauet, Thierry

Journal:

Pharmacological Research

Year:

2018

Language:

english

File:

PDF, 636 KB

english, 2018

6

Toxicities associated with chemotherapy regimens containing a fluoropyrimidine: A real-life evaluation in France

Barin-Le Guellec, Chantal, Lafay-Chebassier, Claire, Ingrand, Isabelle, Tournamille, Jean-François, Boudet, Adeline, Lanoue, Mary-Christine, Defossez, Gautier, Ingrand, Pierre, Perault-Pochat, Marie-C

Journal:

European Journal of Cancer

Year:

2020

Language:

english

File:

PDF, 356 KB

english, 2020

7

Measurement of glomerular filtration rate using a reference method

Chardon, Laurence, Dubourg, Laurence, Barin-Le Guellec, Chantal, Guinard, Francis, Hannedouche, Thierry, Halimi, Jean-Michel, Mariat, Christophe

Journal:

Annales de Biologie Clinique

Year:

2019

File:

PDF, 165 KB

2019

8

Effects of Ischemia-Reperfusion on Tubular Cell Membrane Transporters and Consequences in Kidney Transplantation

Faucher, Quentin, Alarcan, Hugo, Marquet, Pierre, Barin-Le Guellec, Chantal

Journal:

Journal of Clinical Medicine

Year:

2020

File:

PDF, 1.24 MB

2020

9

A Machine Learning Approach to Estimate the Glomerular Filtration Rate in Intensive Care Unit Patients Based on Plasma Iohexol Concentrations and Covariates

Woillard, Jean-Baptiste, Salmon GandonniÃ¨re, Charlotte, Destere, Alexandre, Ehrmann, Stephan, Merdji, Hamid, Mathonnet, Armelle, Marquet, Pierre, Barin-Le Guellec, Chantal

Journal:

Clinical Pharmacokinetics

Year:

2020

File:

PDF, 1.05 MB

2020

10

Pharmacokinetics of rituximab and its clinical use: Thought for the best use?

Guillaume Cartron, Hélène Blasco, Gilles Paintaud, Hervé Watier, Chantal Le Guellec

Journal:

Critical Reviews in Oncology/Hematology

Year:

2007

Language:

english

File:

PDF, 369 KB

english, 2007

11

Agrobacterium rhizogenesmediated transformation of grapevine (Vitis viniferaL.)

Véronique Guellec, Chantal David, Michel Branchard, Jacques Tempé

Journal:

Plant Cell, Tissue and Organ Culture

Year:

1990

Language:

english

File:

PDF, 957 KB

english, 1990

12

Inhibitory effects of anticancer drugs on dextromethorphan-O-demethylase activity in human liver microsomes

Chantal Guellec, Bruno Lacarelle, Jacques Catalin, Alain Durand

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 433 KB

english, 1993

13

Quantification of coproporphyrin isomers I and III in urine by HPLC and determination of their ratio for investigations of Multidrug Resistance Protein 2 (MRP2) function in humans

Renaud Respaud, Isabelle Benz-de Bretagne, Helene Blasco, Jean Sébastien Hulot, Philippe Lechat, Chantal Le Guellec

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 556 KB

english, 2009

14

Bayesian estimation of cyclosporin exposure for routine therapeutic drug monitoring in kidney transplant patients

Hélène Bourgoin, Gilles Paintaud, Matthias Büchler, Yvon Lebranchu, Elisabeth Autret-Leca, France Mentré, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

15

Relationship between 5-fluorouracil exposure and outcome in patients receiving continuous venous infusion with or without concomitant radiotherapy

Maud Beneton, Sophie Chapet, Hélène Blasco, Bruno Giraudeau, Michèle Boisdron-Celle, Régine Deporte-Fety, Fabrice Denis, Bérangère Narcisso, Gilles Calais, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

16

A well-tolerated 5-FU-based treatment subsequent to severe capecitabine-induced toxicity in a DPD-deficient patient

Hélène Blasco, Michéle Boisdron-Celle, Philippe Bougnoux, Gilles Calais, Jean-François Tournamille, Joseph Ciccolini, Elisabeth Autret-Leca, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 442 KB

english, 2008

17

Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

Hélène Blasco, Delphine Senecal, Amélie Le Gouge, Emmanuelle Pinard, Isabelle Benz-de Bretagne, Philippe Colombat, Jean-Sébastien Hulot, Etienne Chatelut, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 790 KB

english, 2010

18

Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal

Denis Garot, Renaud Respaud, Philippe Lanotte, Nicolas Simon, Emmanuelle Mercier, Stephan Ehrmann, Dominique Perrotin, Pierre-François Dequin, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

19

Prediction of methotrexate elimination after high dose infusion in children with acute lymphoblastic leukaemia using a population pharmacokinetic approach

Franck Odoul, Chantal Le Guellec, Jean-Pierre Lamagnère, Dominique Breilh, Marie-Claude Saux, Gilles Paintaud, Elisabeth Autret-Leca

Journal:

Fundamental & Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 726 KB

english, 1999

20

Lack of association between rifampicin plasma concentration and treatment-related side effects in osteoarticular infections

France Roblot, Jean-Marc Besnier, Bruno Giraudeau, Nicolas Simonnard, Annie-Pierre Jonville-Bera, Patrick Coipeau, Patrick Choutet, Elisabeth Autret-Leca, Chantal Le Guellec

Journal:

Fundamental & Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 501 KB

english, 2007

21

Pharmacokinetics of rituximab associated with CHOP chemotherapy in B-cell non-Hodgkin lymphoma

Hélène Blasco, Etienne Chatelut, Isabelle Benz De Bretagne, Nicolas Congy-Jolivet, Chantal Le Guellec

Journal:

Fundamental & Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 182 KB

english, 2009

22

New ipratropium formulation to decrease nebulization time

Caroline Majoral, Laurent Vecellio, Daniel Grimbert, Michèle de Monte, Chantal le Guellec, Valérie Ingremeau, Carole Minois, Emeline Cordeau, Gilles Paintaud, Anouck Steinberg, Patrice Diot

Journal:

Respiratory Medicine

Year:

2007

Language:

english

File:

PDF, 949 KB

english, 2007

23

Vers une personnalisation des traitements par la pharmacogénétique

Anne Tallet, Chantal Le Guellec

Journal:

Actualités Pharmaceutiques

Year:

2011

Language:

french

File:

PDF, 301 KB

french, 2011

24

P-10 Anti-proliferative activity of gemcitabine aerosol

Leblond, Valérie, None, Laurent Vecellio, Bataille, Emmanuelle Boll, Grimbert, Daniel, Beneton, Maud, Le Guellec, Chantal, Lemarie, Etienne

Journal:

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

25

Application of a Gamma Model of Absorption to Oral Cyclosporin

Dr Jean Debord, Eléonore Risco, Michel Harel, Yannick Le Meur, Mathias Büchler, Gérard Lachâtre, Chantal Le Guellec, Pierre Marquet

Journal:

Clinical Pharmacokinetics

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

26

A Double Absorption-Phase Model Adequately Describes Mycophenolic Acid Plasma Profiles inDe NovoRenal Transplant Recipients Given Oral Mycophenolate Mofetil

Aurélie Prémaud, Jean Debord, Annick Rousseau, Yannick Le Meur, Olivier Toupance, Yvon Lebranchu, Guillaume Hoizey, Chantal Le Guellec, Prof. Pierre Marquet

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 204 KB

english, 2005

27

Population Pharmacokinetics of Ganciclovir Following Administration of Valganciclovir in Paediatric Renal Transplant Patients

Wei Zhao, Véronique Baudouin, Daolun Zhang, Georges Deschênes, Chantal Le Guellec, Prof. Evelyne Jacqz-Aigrain

Journal:

Clinical Pharmacokinetics

Year:

2009

Language:

english

File:

PDF, 174 KB

english, 2009

28

Population Pharmacokinetics and Bayesian Estimation of Mycophenolic Acid Concentrations in Stable Renal Transplant Patients

Dr Chantal Le Guellec, Hélène Bourgoin, Matthias Büchler…

Journal:

Clinical Pharmacokinetics

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

29

Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance

Benz-de Bretagne, Isabelle, Zahr, Noël, Le Gouge, Amélie, Hulot, Jean-Sébastien, Houillier, Caroline, Hoang-Xuan, Khe, Gyan, Emmanuel, Lissandre, Séverine, Choquet, Sylvain, Le Guellec, Chantal

Journal:

British Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

30

Population pharmacokinetics of rituximab with or without plasmapheresis in kidney patients with antibody-mediated disease

Puisset, Florent, White-Koning, Mélanie, Kamar, Nassim, Huart, Antoine, Haberer, Frédérique, Blasco, Hélène, Le Guellec, Chantal, Lafont, Thierry, Grand, Anaïs, Rostaing, Lionel, Chatelut, Etienne, Po

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 933 KB

english, 2013

31

Unusual Pharmacokinetics of Intravitreal and Systemic Voriconazole in a Patient with Scedosporium Apiospermum Endophthalmitis

Nochez, Yannick, Arsene, Sophie, Guellec, Chantal Le, Bastides, Frédéric, Morange, Virginie, Chaumais, Marie Camille, Pisella, Pierre-Jean

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2008

Language:

english

File:

PDF, 103 KB

english, 2008

32

Irreversible hepatotoxicity after administration of trabectedin to a pleiomorphic sarcoma patient with a rare ABCC2 polymorphism: a case report

Laurenty, Anne-Pascale, Thomas, Fabienne, Chatelut, Etienne, Bétrian, Sarah, Guellec, Chantal Le, Hennebelle, Isabelle, Guellec, Sophie Le, Chevreau, Christine

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 900 KB

english, 2013

33

First Dose in Neonates: Are Juvenile Mice, Adults and In Vitro–In Silico Data Predictive of Neonatal Pharmacokinetics of Fluconazole

Zhao, Wei, Le Guellec, Chantal, Benjamin, Daniel K., Hope, William W., Bourgeois, Thomas, Watt, Kevin M., van den Anker, Johannes N., Matrot, Boris, Saxen, Harri, Hoppu, Kalle, Manzoni, Paolo, Jacqz-A

Journal:

Clinical Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 926 KB

english, 2014

34

Assessing the Metabolic Effects of Calcineurin Inhibitors in Renal Transplant Recipients by Urine Metabolic Profiling

Diémé, Binta, Halimi, Jean Michel, Emond, Patrick, Büchler, Matthias, Nadal-Desbarat, Lydie, Blasco, Hélène, Le Guellec, Chantal

Journal:

Transplantation Journal

Year:

2014

Language:

english

File:

PDF, 2.83 MB

english, 2014

35

A New Rapid and Sensitive LC-MS Assay for the Determination of Sorafenib in Plasma: Application to a Patient Undergoing Hemodialysis

Bobin-Dubigeon, Christine, Heurgue-Berlot, Alexandra, Bouché, Olivier, Amiand, Marie-Bernadette, Le Guellec, Chantal, Bard, Jean-Marie

Journal:

Therapeutic Drug Monitoring

Year:

2011

Language:

english

File:

PDF, 173 KB

english, 2011

36

A Case of Severe Toxicity During Coadministration of Vincristine and Piperacillin

Le Guellec, Chantal, Benz-de Bretagne, Isabelle, Jonville-Bera, Annie-Pierre, Tarfaoui, Naoual, Andres, Christian R., Gendrot, Chantal, Jourdain, Anne

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

37

Urinary Elimination of Coproporphyrins Is Dependent on ABCC2 Polymorphisms and Represents a Potential Biomarker of MRP2 Activity in Humans

Benz-de Bretagne, Isabelle, Respaud, Renaud, Vourc'h, Patrick, Halimi, Jean-Michel, Caille, Agnès, Hulot, Jean-Sébastien, Andres, Christian R., Le Guellec, Chantal

Journal:

Journal of Biomedicine and Biotechnology

Year:

2011

Language:

english

File:

PDF, 343 KB

english, 2011

38

Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1 H NMR and GC-MS approach

Kienana, Muhrez, Lydie, Nadal-Desbarats, Jean-Michel, Halimi, Binta, Dieme, Matthias, Büchler, Patrick, Emond, Hélène, Blasco, Chantal, Le Guellec

Journal:

Molecular BioSystems

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

39

Inhaled Fenoterol–Ipratropium Bromide in Mechanically Ventilated Patients with Chronic Obstructive Pulmonary Disease

GUERIN, CLAUDE, CHEVRE, ARNAUD, DESSIRIER, PIERRE, PONCET, THIERRY, BECQUEMIN, MARIE-HELENE, DEQUIN, PIERRE FRANÇOIS, LE GUELLEC, CHANTAL, JACQUES, DIDIER, FOURNIER, GERARD

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1999

Language:

english

File:

PDF, 97 KB

english, 1999

40

Safety study of Ciprofloxacin in newborn mice

Bourgeois, Thomas, Delezoide, Anne-Lise, Zhao, Wei, Guimiot, Fabien, Adle-Biassette, Homa, Durand, Estelle, Ringot, Maud, Gallego, Jorge, Storme, Thomas, Le Guellec, Chantal, Kassaï, Behrouz, Turner,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1011 KB

english, 2016

41

Glucuronidation of Propofol in Microsomal Fractions from Various Tissues and Species Including Humans

Le Guellec, Chantal, Lacarelle, Bruno, Villard, Pierre-Henri, Point, Huguette, Catalin, Jacques, Durand, Alain

Journal:

Anesthesia & Analgesia

Year:

1995

Language:

english

File:

PDF, 1.59 MB

english, 1995

42

Endogenous metabolites that are substrates of Organic Anion Transporter’s (OATs) predict methotrexate clearance

Kienana, Muhrez, Benz-de Bretagne, Isabelle, Nadal-Desbarats, Lydie, Blasco, Hélène, Gyan, Emmanuel, Choquet, Sylvain, Montigny, Frédéric, Emond, Patrick, Barin-Le Guellec, Chantal

Journal:

Pharmacological Research

Year:

2016

File:

PDF, 805 KB

2016

43

Suivi thérapeutique pharmacologique de la clozapine

Le Guellec, Chantal, Delhotal, Brigitte

Journal:

EMC - Biologie Médicale

Year:

2006

Language:

french

File:

PDF, 97 KB

french, 2006

44

Therapeutic Drug Monitoring of HIV Protease Inhibitors Using High-Performance Liquid Chromatography With Ultraviolet or Photodiode Array Detection

Leibenguth, Patrice, Le Guellec, Chantal, Besnier, Jean-Marc, Bastides, Frederic, Macé, Muriel, Gaudet, Marie-Laure, Autret-Leca, Elisabeth, Paintaud, Gilles

Journal:

Therapeutic Drug Monitoring

Year:

2001

Language:

english

File:

PDF, 205 KB

english, 2001

45

Suivi thérapeutique pharmacologique de la théophylline

Royer-Morrot, Marie-José, Sciaudeau, Sophie, Le Guellec, Chantal, Boulieu, Roselyne

Journal:

EMC - Biologie Médicale

Year:

2006

Language:

french

File:

PDF, 110 KB

french, 2006

46

Glucuronidation of Propofol in Microsomal Fractions from Various Tissues and Species Including Humans

Le Guellec, Chantal, Lacarelle, Bruno, Villard, Pierre-Henri, Point, Huguette, Catalin, Jacques, Durand, Alain

Journal:

Anesthesia & Analgesia

Year:

1995

Language:

english

File:

PDF, 1.59 MB

english, 1995

47

Suivi thérapeutique pharmacologique du carboplatine

Canal, Pierre, Chatelut, Etienne, Rousseau, Annick, Marquet, Pierre, Le Guellec, Chantal

Journal:

EMC - Biologie Médicale

Year:

2006

Language:

french

File:

PDF, 110 KB

french, 2006

48

Suivi thérapeutique pharmacologique de l'acide mycophénolique

Marquet, Pierre, Risco, Éléonore, Le Guellec, Chantal, Billaud, Éliane

Journal:

EMC - Biologie Médicale

Year:

2006

Language:

french

File:

PDF, 118 KB

french, 2006

49

Traitements personnalisés grâce à la pharmacogénétique : niveaux de preuve et de recommandations du Réseau national de pharmacogénétique (RNPGx)

Picard, Nicolas, Boyer, Jean-Christophe, Etienne-Grimaldi, Marie-Christine, Barin-Le Guellec, Chantal, Thomas, Fabienne, Loriot, Marie-Anne

Journal:

Year:

2017

Language:

french

File:

PDF, 488 KB

french, 2017

50

Niveau de preuve du suivi thérapeutique pharmacologique du cisplatine

Hulin, Anne, Royer, Bernard, Chatelut, Etienne, Le Guellec, Chantal

Journal:

Year:

2010

Language:

french

File:

PDF, 115 KB

french, 2010